Skip to main content
Entomology 2021 Main banner
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Presentation Icons
In-Person
In-Person
Livestream
Livestream
On-Demand
On-Demand
Student Competition
Student Competition
Video Chat
Video Chat
Ticketed Event
Ticketed Event
Poster Icons
Student Competition
Student Competition
In-Person
In-Person
Poster
Poster
On-Demand
On-Demand
Q&A ViewAttendees 5

Physiology, Biochemistry, and Toxicology

Section Symposium

A Functional Genomics Approach to Insect Overwintering and Cold Tolerance

Suppressed expression of oxidoreductin-like protein, oxidor, increases follicle degeneration and decreases survival during the overwintering diapause of the mosquito Culex pipiens

Tuesday, November 2, 2021
9:15 AM - 9:30 AM MT
Location: Colorado Convention Center, Meeting Room 405-407
In-Person
Enhanced stress tolerance is one of the hallmarks of diapause, and several genes encoding stress-related proteins were revealed in our previous ChIP-seq analysis as being under the control of FOXO. One is an oxidoreductin-like protein, a protein likely involved in reducing oxidative stress during mosquito diapause. Here, we report that oxidoreductin-like protein is involved in overwintering stress tolerance in diapausing mosquitoes. The gene that encodes oxidoreductin-like protein (oxidor) was suppressed by RNAi, and the proportion of degenerating follicles were assessed. Consequently, suppression of the gene encoding oxidoreductin-like protein with RNAi significantly increased the proportion of degenerating follicles in diapausing mosquitoes. The suppression of the oxidor gene also significantly reduced the survivability of diapausing females, which indicates that oxidoreductin-like protein plays a key role in protecting tissues during overwintering diapause.